Quarterly report pursuant to Section 13 or 15(d)

10. STOCK-BASED COMPENSATION (Details - Option activity)

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10. STOCK-BASED COMPENSATION (Details - Option activity) - Options [Member] - USD ($)
6 Months Ended 12 Months Ended
Jun. 30, 2016
Dec. 31, 2015
Share-based compensation activity    
Options outstanding, beginning balance 9,799,036  
Options outstanding, granted 1,210,000  
Options outstanding, forfeited (13,015)  
Options outstanding, expired (76,036)  
Options outstanding, ending balance 10,919,985 9,799,036
Options outstanding, exercisable 7,616,746  
Options outstanding, unvested 3,303,239  
Options outstanding, vested or expected to vest 10,919,985  
Weighted average exercise price, beginning balance $ 1.97  
Weighted average exercise price, granted .42  
Weighted average exercise price, forfeited .73  
Weighted average exercise price, expired 2.82  
Weighted average exercise price, ending balance 1.80 $ 1.97
Weighted average exercise price, exercisable 2.10  
Weighted average exercise price, unvested 1.10  
Weighted average exercise price, vested or expected to vest $ 1.80  
Weighted average remaining contract term, ending term 8 years 10 months 2 days 9 years 2 months 12 days
Weighted average remaining contract term, exercisable 8 years 7 months 28 days  
Weighted average remaining contract term, unvested 9 years 3 months 4 days  
Weighted average remaining contract term, vested or expected to vest 8 years 10 months 2 days  
Aggregate intrinsic value, ending balance $ 200,200 $ 57,800
Aggregate intrinsic value, exercisable 140,450  
Aggregate intrinsic value, unvested 59,750  
Aggregate intrinsic value, vested or expected to vest $ 200,200