Quarterly report pursuant to Section 13 or 15(d)

9. STOCK-BASED COMPENSATION (Details - Option activity)

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9. STOCK-BASED COMPENSATION (Details - Option activity) - Options [Member] - USD ($)
 3 Months Ended 12 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Share-based compensation activity    
Options outstanding, beginning balance 12,841,000  
Options outstanding, granted 8,747,000  
Options outstanding, exercised 0  
Options outstanding, forfeited (6,100,278)  
Options outstanding, expired (12,500)  
Options outstanding, ending balance 15,475,222 12,841,000
Options outstanding, exercisable 10,105,687  
Options outstanding, unvested 5,369,535  
Options outstanding, vested or expected to vest 15,475,222  
Weighted average exercise price, beginning balance $ 1.57  
Weighted average exercise price, granted 0.38  
Weighted average exercise price, exercised 0.00  
Weighted average exercise price, forfeited 2.64  
Weighted average exercise price, expired 0.73  
Weighted average exercise price, ending balance 0.48 $ 1.57
Weighted average exercise price, exercisable 0.52  
Weighted average exercise price, unvested 0.40  
Weighted average exercise price, vested or expected to vest $ 0.48  
Weighted average remaining contract term, ending term 8 years 6 months 29 days 8 years 6 months 15 days
Weighted average remaining contract term, exercisable 8 years 1 month 21 days  
Weighted average remaining contract term, unvested 9 years 4 months 28 days  
Weighted average remaining contract term, vested or expected to vest 8 years 6 months 29 days  
Aggregate intrinsic value, ending balance $ 500,675 $ 415,135
Aggregate intrinsic value, exercisable 307,602  
Aggregate intrinsic value, unvested 193,073  
Aggregate intrinsic value, vested or expected to vest $ 500,675